Opportunity Information: Apply for RFA ES 22 001
Maintaining and Enriching Environmental Epidemiology Cohorts to Support Scientific and Workforce Diversity (RFA-ES-22-001) is a National Institutes of Health (NIH), National Institute of Environmental Health Sciences (NIEHS) funding opportunity that uses a cooperative agreement mechanism (U24) and does not allow clinical trials. The main idea is to protect and strengthen existing Environmental Epidemiology Cohorts (EECs) by helping them keep core operations running while also upgrading the shared resources that make these cohorts more useful to the broader research community. In practice, the FOA is aimed at ensuring that long-running, high-value cohort studies do not stall due to infrastructure gaps and that the data they produce can be more easily found, combined, and reused for environmental health research.
The FOA has two tightly linked goals. First, it supports the maintenance and enrichment of resource infrastructure for existing cohorts, meaning applicants are expected to propose practical activities that keep cohorts viable and scientifically productive. This can include strengthening cohort operations and improving the cohort as a research platform, such as updating systems and procedures that support continued follow-up, improving how exposure and health outcome data are captured over time, and enhancing the supporting infrastructure that keeps cohort data reliable and usable. Second, it emphasizes upgrading data management and data sharing in ways that promote widespread sharing and collaboration. The intent is not just to store data, but to make data more harmonizable, better documented, and more accessible so that outside researchers can collaborate and conduct additional analyses, including analyses that were not part of the original cohort plans.
A major distinguishing feature of this opportunity is its strong focus on equity and inclusion in both science and workforce development. The FOA explicitly seeks to broaden participation in environmental epidemiology by making data sharing and collaboration more inclusive of under-resourced minority-serving institutions (MSIs) and under-represented minority researchers. The overarching objective is to maximize NIEHS investments in cohorts by improving the quality and completeness of data on under-represented populations in environmental health studies, while also strengthening workforce diversity. In other words, the program is designed to improve who is represented in the data and who gets access to the data and collaborative opportunities that can drive publications, grants, and career advancement.
Because this is a U24 cooperative agreement, awardees should generally expect substantial NIH/NIEHS involvement compared to a standard research grant. Cooperative agreements are commonly used when the funder anticipates active partnership in coordinating activities, setting priorities, promoting common standards, and ensuring that products such as shared datasets, documentation, and other cohort resources meet community needs. The emphasis on broad data sharing and collaboration also signals that applicants should be prepared to align with NIH expectations around data stewardship, interoperability, and responsible sharing, including the kinds of documentation and governance structures that make sharing workable in real-world settings.
Eligibility is broad and spans many public and private organizational types. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education and private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized; nonprofits with and without 501(c)(3) status (excluding institutions of higher education under that category); for-profit organizations other than small businesses; and small businesses. The FOA also highlights inclusion of specific organization types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. At the same time, non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply, though foreign components, as defined by the NIH Grants Policy Statement, are allowed. This structure allows U.S.-based applicants to incorporate certain international elements when justified, while keeping the applicant organization and primary award framework domestic.
From an administrative standpoint, the opportunity is categorized as discretionary funding, with an activity focus on environment and health (CFDA 93.113). The listed award ceiling is $250,000, indicating that proposed work should be scoped toward maintain-and-enhance functions rather than launching entirely new, large-scale cohort initiatives. The original closing date was November 4, 2022, and the FOA was created January 3, 2022, which is useful context for understanding that this was a time-limited solicitation rather than an always-open program announcement.
Overall, this FOA is best read as an effort to keep valuable environmental epidemiology cohorts strong and relevant while modernizing how cohort data are managed and shared, with a deliberate push to ensure that the benefits of these cohort investments extend to researchers and institutions that have historically been under-resourced or under-represented. The end goal is a more collaborative, more diverse environmental epidemiology ecosystem where cohort data are better curated, more broadly usable, and more representative of populations that need to be included to answer environmental health questions fairly and accurately.Apply for RFA ES 22 001
- The National Institutes of Health in the environment, health sector is offering a public funding opportunity titled "Maintaining and Enriching Environmental Epidemiology Cohorts to Support Scientific and Workforce Diversity (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113.
- This funding opportunity was created on 2022-01-03.
- Applicants must submit their applications by 2022-11-04. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Revolutionizing Innovative, Visionary Environmental Health Research (RIVER) (R35 Clinical Trial Optional) Apply for RFA ES 22 002 Funding Number: RFA ES 22 002 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R21-Clinical Trial Not Allowed) Apply for PAR 22 138 Funding Number: PAR 22 138 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R01-Clinical Trial Not Allowed) Apply for PAR 22 137 Funding Number: PAR 22 137 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 22 004 Funding Number: RFA ES 22 004 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $200,000 |
| Research to Action: Assessing and Addressing Community Exposures to Environmental Contaminants (R01 Clinical Trial Optional) Apply for PAR 22 210 Funding Number: PAR 22 210 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Centers for Oceans and Human Health 4: Impacts of Climate Change on Oceans and Great Lakes (COHH4) (P01 Clinal Trial Optional) Apply for RFA ES 22 005 Funding Number: RFA ES 22 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $950,000 |
| Biological Basis for how Environmental Exposures Impact Risk for Psychiatric Disorders (R01 Clinical Trial Not Allowed) Apply for RFA ES 22 008 Funding Number: RFA ES 22 008 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $400,000 |
| Biological Basis for how Environmental Exposures Impact Risk for Psychiatric Disorders (R21 Clinical Trial Not Allowed) Apply for RFA ES 22 009 Funding Number: RFA ES 22 009 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $275,000 |
| Utilizing Telomere Status to Reveal Molecular Mechanisms Underlying Susceptibility and Resiliency in Response to Environmental Exposures (R01 Clinical Trial Not Allowed) Apply for RFA ES 22 007 Funding Number: RFA ES 22 007 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Environmental Health Sciences Core Centers (EHSCC) (P30 Clinical Trial Optional) Apply for RFA ES 22 010 Funding Number: RFA ES 22 010 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Accelerating Data and Metadata Standards in the Environmental Health Sciences (R24 Clinical Trial Not Allowed) Apply for RFA ES 23 002 Funding Number: RFA ES 23 002 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $400,000 |
| Maintaining and Enriching Environmental Epidemiology Cohorts to Support Scientific and Workforce Diversity (U24 Clinical Trial Not Allowed) Apply for RFA ES 23 003 Funding Number: RFA ES 23 003 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 23 005 Funding Number: RFA ES 23 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Strategies for Responsibly Reporting Back Environmental Health and Non-Genomic Research Results (R01 Clinical Trial Optional) Apply for RFA ES 23 006 Funding Number: RFA ES 23 006 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| CCRP Initiative: Chemical Threat Agent Exposure Resource and Coordination Core (ExRC) (U2C Clinical Trial Not Allowed) Apply for RFA ES 23 009 Funding Number: RFA ES 23 009 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $750,000 |
| Undergraduate Research Education Program (UP) to Enhance Diversity in the Environmental Health Sciences (R25 Clinical Trial Not Allowed) Apply for RFA ES 23 012 Funding Number: RFA ES 23 012 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $125,000 |
| Hazardous Materials Worker Health and Safety Training (U45 Clinical Trials Not Allowed) Apply for RFA ES 24 001 Funding Number: RFA ES 24 001 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 24 003 Funding Number: RFA ES 24 003 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| HAZMAT Training at DOE Nuclear Weapons Complex (UH4 Clinical Trial Not Allowed) Apply for RFA ES 24 002 Funding Number: RFA ES 24 002 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed) Apply for RFA ES 24 005 Funding Number: RFA ES 24 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
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